節目分成三部分:名人新聞與八卦、即將上映的電影與電視節目以及娛樂產業相關新聞。另外更特別聚焦在國際名人。
E! News mainly reports on celebrity news and gossip, along with previews of upcoming films and television shows, regular segments about all of those three subjects, and some news about the industry in general. Featuring specials on international atrists.